5-HTP
February 19, 2009 by About Supplements
Filed under Supplement News
5-HTP
What is it?
5-hydroxytryptophan (5HTP) is a precursor to the neuro-transmitter serotonin. 5HTP can be produced synthetically, but many supplements contain 5HTP derived from the Griffonia simplicifolia seed.
What is it supposed to do?
As mentioned above, 5HTP converts into the neuro-transmitter serotonin in both the brain and the peripheral tissues. As most people know, serotonin is a very hot topic and area of research right now due to serotonin’s effects on mood, depression, etc. Serotonin is probably the most studied neurotransmitter since it has been found to be involved in a wide range of psychological and biological functions. Serotonin ( also called 5-hydroxytryptamine or 5-HT) is involved with mood, anxiety, and appetite. Elevated levels of serotonin can cause relaxation and reduced anxiety. Low serotonin levels are associated with low mood, increased anxiety (hence the current popularity of the SSRI drugs such as Prozac and others), and poor appetite control. Needless to say, Increased brain serotonin levels are associated with an improved ability of people to cope with stress, whereas a decline in serotonin activity is associated with depression and anxiety. Elevated levels of serotonin in the body often result in the relief of depression, as well as substantial reduction in pain sensitivity, anxiety and stress. It has also been theorized that a diet-induced increase in tryptophan will increase brain serotonin levels, while a diet designed for weight loss (e.g., a diet that reduces calories) may lead to a reduction of brain serotonin levels due to reduced substrate for production and a reduction in carbohydrates. Many people on a reduced calorie intake in an attempt to lose weight find they are often ill tempered and more anxious. Reductions in serotonin may be partially to blame here. The basic theory is 5HTP increases brain serotonin levels which should lead to improved mood states and a reduction in food intakes.
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