February 19, 2009 by About Supplements  
Filed under Body Building Supplements


What is it?

HMB is actually a metabolite of the amino acid L-leucine. L-leucine is one of three amino acids known as the branched chain amino acids or BCAA (isoleucine and valine being the other two).

It has been known for a long time that BCAA play a critical role in the turn over of lean body tissues (muscle) and is muscle sparing (i.e. anti-catabolic) in a variety of muscle wasting states. Of the three BCAA, L-leucine appears to be the most important to preserving hard earned muscle mass and intense exercise and certain disease states have been shown to eat up a great deal of L-leucine. So far so good!

The main drawback of L-leucine is the fact that you must use large amounts of this amino acid to get a positive effect, making it both expensive and impractical. Many studies that showed benefits were in fact done intravenously and used as much as 5 grams per hour of L-leucine!

That, my friend, is a lot of leucine.

So, it was theorized there might be a metabolite of this ultra important amino acid that was responsible for many of the positive effects of L-leucine but could be taken in far lower doses and by mouth (as opposed to having a tube stuck in your arm). That metabolite appears to be HMB.

During stressful conditions, animals will often lose weight and/or become quite ill. Some even die. This of course can be quite expensive for any company trying to make a living from these animals in one way or another. When animals were fed HMB a large reduction in mortality rates, increases in muscle mass, and improvements in immune function in the animals fed HMB, were found.

For more detailed information, including effectiveness, dosages, possible side effects as well as independent science based reviews of over 60 ingredients for gaining muscle mass we recommend the well respected Will Brink’s supplement review module found in his complete BodyBuilding Revealed program.

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